High-dose vitamin D intake helps against chronic intestinal inflammation

High-dose vitamin D intake helps against chronic intestinal inflammation

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Inflammatory bowel diseases are a common disease

Inflammatory bowel disease (IBD) is one of the most widespread chronic diseases today. In Europe alone, three million people are affected. Most ill patients suffer from ulcerative colitis and Crohn's disease. What influence does vitamin D have on this course of the disease?

Vitamin D deficiency as a trigger?

Vitamin D deficiency is often diagnosed in patients with chronic diseases, including those with inflammatory bowel diseases such as Crohn's disease and ulcerative colitis. A research team from the Hospital of Jinan in Guangzhou (China) recently showed in its study that vitamin D has a positive effect on the intestinal mucosa. This showed less pathological changes when the vitamin D supply was better. The study was published in the journal Medicine.

Vitamin D has a positive effect on the intestinal mucosa

The researchers report that vitamin D has anti-inflammatory properties and promotes the regeneration of the intestinal mucosa and thus also improves the symptoms and quality of life of people with chronic inflammatory bowel diseases.

Dosage of vitamin D

The evaluation showed that the addition of vitamin D supplements reliably increased the vitamin D level, but that high-dose therapy increased the level better than that of low doses. With the high-dose therapy, doses of 1,000 to 10,000 IU were administered. The researchers expressly point out that officially only the daily intake of 600 IU (maximum 4,000 IU) is recommended, but this low dose is not always sufficient for people who already have a deficiency.

Side effects with vitamin D

Side effects were only recorded in a few test subjects and only in the high-dose variant. In the same breath, however, the researchers emphasize that the benefits of this therapy far outweigh the benefits. The side effects listed are rather harmless events such as thirst, nausea, dry mouth and tiredness. However, it is also not clear whether these symptoms are actually due to vitamin D intake.

Vitamin D is helpful for inflammatory bowel diseases

It was particularly important in the result of the analysis presented that the intake of vitamin D could reduce the number of relapses. However, there was no difference here between high and low vitamin D doses. It was obviously decisive that vitamin D supplementation was even considered. The researchers concluded that the intake of vitamin D is absolutely recommended to accompany the treatment of inflammatory bowel diseases. (fm)

Author and source information

Video: 8 Signs Your Body Is Begging for Vitamin D (December 2022).